Title
Study of the Features of in Vitro Degradation of PCL, PLA, and Polymer 3D Scaffolds in Static and Dynamic Conditions
Authors
[ 1 ] Wydział Inżynierii Mechanicznej, Politechnika Poznańska | [ SzD ] doctoral school student
Scientific discipline (Law 2.0)
Year of publication
2024
Chapter type
chapter in monograph / paper
Publication language
english
Keywords
EN
- biomaterials
Abstract
EN Biomaterials and polymers (HA, PLA, and PCL) in recent decades have become a real alternative to traditional metals in orthopedics, surgery, and cardiac surgery due to the possibility of complete elimination after performing their function. The possibility of creating 3D structures takes modern science to a completely different level. However, the presence of several disadvantages of metal structures, such as uncontrolled resorption, the discrepancy in mechanical properties (Young’s modulus, etc.), as well as the lack of absolute biological neutrality of foreign material in bone tissue, is the main problem of the clinical use of degrading alloys, in connection with the possibility of the development of many clinical complications. To eliminate this problem, various methods are used: creating new alloys and post-cast processing, forming a protective coating, or replacing the metal base with a hydroxyapatite one, as well as the use of 3D printing technologies. This work aims to study and research the features and speed of degradation of biodegradable alloys under in vitro conditions. Biodegradable biopolymer implants and medical devices (stents, occluders, suture material, etc.) can be widely used in surgery, cardiovascular surgery, and orthopedics. Considering the increasing number of reconstructive operations and the improvement of operative techniques, biodegradable scaffolds have a potentially wide range of widespread applications under the conditions of reducing the cost and controlling the biodegradation rate. Control of the corrosive properties of biopolymers will allow the creation of a fundamentally new product that will be able to compete with the world’s leading manufacturers of medical devices.
Date of online publication
16.07.2024
Pages (from - to)
308 - 323
Ministry points / chapter
20
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