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Article

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Title

Quantifying of thallium in Shilajit and its supplements to unveil the potential risk of consumption of this popular traditional medicine

Authors

[ 1 ] Wydział Technologii Chemicznej, Politechnika Poznańska | [ 2 ] Instytut Chemii i Elektrochemii Technicznej, Wydział Technologii Chemicznej, Politechnika Poznańska | [ D ] phd student | [ P ] employee

Scientific discipline (Law 2.0)

[7.6] Chemical sciences

Year of publication

2025

Published in

BMC Chemistry

Journal year: 2025 | Journal volume: vol. 19

Article type

scientific article

Publication language

english

Keywords
EN
  • Shilajit
  • Thallium
  • Toxicity
  • Supplementary drugs
  • Natural substance
  • Flow-injection differential-pulse anodic stripping voltammetry
Abstract

EN Shilajit, a natural substance used in traditional and modern medicine, has gained prominence as a vital component in dietary supplements. Concerns regarding its use in complementary medicine have arisen due to limited information regarding its composition. Considering thallium’s well-known toxicity, this study employs flow - injection differential-pulse anodic stripping voltammetry to accurately quantify thallium in natural Shilajit and Shilajit-based commercial supplements from various regions. The limit of detection and limit of quantification were determined as 6.58 × 10− 3 µg.mL− 1 and 1.98 × 10− 2 µg.mL− 1, respectively. Thallium contents were detected up to 0.226 µg.g− 1 in natural Shilajit, but mainly in the range of a few tenths of µg.g− 1. Thallium contents were found up to 0.5 µg.g− 1 in the supplements studied. Consumption of one pill of supplement, introduces up to 0.095 µg of Tl to the body. Notably, the concentration of thallium in some supplements was higher than in crude Shilajit, raising concerns about the potential health risks associated with long-term consumption. This study underscores potential health risks associated with thallium in both Shilajit and supplements. Regular monitoring and standardized testing are essential to ensure compliance with safe thallium limits, protecting consumers against potential thallium poisoning.

Date of online publication

18.01.2025

Pages (from - to)

20-1 - 20-8

DOI

10.1186/s13065-025-01384-7

URL

https://doi.org/10.1186/s13065-025-01384-7

Comments

Article number: 20

License type

CC BY-NC-ND (attribution - noncommercial - no derivatives)

Open Access Mode

open journal

Open Access Text Version

final published version

Date of Open Access to the publication

at the time of publication

Full text of article

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Access level to full text

public

Ministry points / journal

70

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