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Article

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Title

Recent Developments in Deep Eutectic Solvents Applications in Liquid Chromatography: 2019–2025

Authors

[ 1 ] Wydział Inżynierii Środowiska i Energetyki, Politechnika Poznańska | [ SzD ] doctoral school student

Scientific discipline (Law 2.0)

[2.10] Environmental engineering, mining and energy

Year of publication

2025

Published in

Journal of Separation Science

Journal year: 2025 | Journal volume: vol. 48 | Journal number: iss. 5

Article type

scientific article

Publication language

english

Keywords
EN
  • deep eutectic solvents
  • green chemistry
  • liquid chromatography
  • mobile phase additive
  • separation efficiency
  • stationary phase modification
Abstract

EN Deep eutectic solvents (DES) are used as mobile phase and stationary phase modifiers, or as for the stationary phase itself for thinlayer/liquid/supercritical chromatography. Their specific properties can improve the separation selectivity, reduce peak tailing,and shorten the separation time. In terms of environmental impact, the advantages of DES are based on their biodegradability,recyclability, and stability in terms of mechanical/chemical/thermal properties. The disadvantages are related to higher viscosityand degradation in aqueous solutions. This review focuses on works that have been published since 2019, the year the excellentcomprehensive review by Cai and Qiu was printed. Selected parameters are discussed that should be considered when DES arepreferred over commonly used mobile and stationary phases due to green chemistry trends, while taking into account theirlimitations in modern LC separations. This review also centres on critical aspects of DES applications in the field of liquid andsupercritical fluid chromatographic separations.

Pages (from - to)

e70160-1 - e70160-9

DOI

10.1002/jssc.70160

URL

https://analyticalsciencejournals.onlinelibrary.wiley.com/doi/10.1002/jssc.70160

Comments

Article Number: e70160

License type

CC BY (attribution alone)

Open Access Mode

czasopismo hybrydowe

Open Access Text Version

final published version

Date of Open Access to the publication

at the time of publication

Ministry points / journal

70

Impact Factor

2,8 [List 2023]

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