Recent Developments in Deep Eutectic Solvents Applications in Liquid Chromatography: 2019–2025
[ 1 ] Wydział Inżynierii Środowiska i Energetyki, Politechnika Poznańska | [ SzD ] doctoral school student
2025
scientific article
english
- deep eutectic solvents
- green chemistry
- liquid chromatography
- mobile phase additive
- separation efficiency
- stationary phase modification
EN Deep eutectic solvents (DES) are used as mobile phase and stationary phase modifiers, or as for the stationary phase itself for thinlayer/liquid/supercritical chromatography. Their specific properties can improve the separation selectivity, reduce peak tailing,and shorten the separation time. In terms of environmental impact, the advantages of DES are based on their biodegradability,recyclability, and stability in terms of mechanical/chemical/thermal properties. The disadvantages are related to higher viscosityand degradation in aqueous solutions. This review focuses on works that have been published since 2019, the year the excellentcomprehensive review by Cai and Qiu was printed. Selected parameters are discussed that should be considered when DES arepreferred over commonly used mobile and stationary phases due to green chemistry trends, while taking into account theirlimitations in modern LC separations. This review also centres on critical aspects of DES applications in the field of liquid andsupercritical fluid chromatographic separations.
e70160-1 - e70160-9
Article Number: e70160
CC BY (attribution alone)
czasopismo hybrydowe
final published version
at the time of publication
70
2,8 [List 2023]