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Article

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Title

Ultrasound-assisted microextraction: Advancements, applications, and future directions in analytical chemistry

Authors

[ 1 ] Instytut Chemii i Elektrochemii Technicznej, Wydział Technologii Chemicznej, Politechnika Poznańska | [ P ] employee

Scientific discipline (Law 2.0)

[7.6] Chemical sciences

Year of publication

2026

Published in

TrAC Trends in Analytical Chemistry

Journal year: 2026 | Journal volume: vol. 194, Part B

Article type

scientific article

Publication language

polish

Keywords
EN
  • Ultrasound-assisted microextractionSample preparationIonic liquidsDeep eutectic solventsGreen chemistry
Abstract

EN Ultrasound technology has become a powerful tool in modern analytical chemistry, particularly for accelerating and miniaturizing sample preparation processes. This review systematically summarizes the progress in ultrasound-assisted microextraction techniques, including dispersive liquid–liquid, emulsification, and solid- or sorbent-based microextractions. The discussion integrates mechanistic understanding of acoustic cavitation and microstreaming with their practical influence on extraction efficiency, enrichment factors, and analyte stability. Special attention is given to the use of ionic liquids, deep eutectic solvents, and magnetic deep eutectic solvents as environmentally benign extractants. The review highlights current trends toward greener, faster, and automatable analytical workflows, while critically addressing limitations such as uneven energy distribution and sonochemical degradation. Finally, key challenges and future directions are outlined, including quantitative modeling of cavitation effects and the development of smart ultrasound-assisted platforms for automated, high-throughput sample preparation.

Date of online publication

12.11.2025

Pages (from - to)

118535-1 - 118535-34

DOI

10.1016/j.trac.2025.118535

URL

https://doi.org/10.1016/j.trac.2025.118535

Comments

Article number: 118535

Ministry points / journal

140

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