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Article


Title

Antibacterial Films Based on MOF Composites that Release Iodine Passively or Upon Triggering by Near-Infrared Light

Authors

[ 1 ] Instytut Inżynierii Materiałowej, Wydział Inżynierii Materiałowej i Fizyki Technicznej, Politechnika Poznańska | [ P ] employee

Scientific discipline (Law 2.0)

[2.7] Materials engineering

Year of publication

2022

Published in

Advanced Functional Materials

Journal year: 2022 | Journal volume: vol. 32 | Journal number: no. 19

Article type

scientific article

Publication language

english

Keywords
EN
  • antimicrobial
  • composites
  • gold nanorods
  • iodine
  • metal-organic frameworks
  • photothermal
  • triggered release
Abstract

EN Multidrug-resistant bacteria have become a global health problem for which new prophylactic strategies are now needed, including surface-coatings for hospital spaces and medical equipment. This work reports the preparation and functional validation of a metal-organic framework (MOF) based composite for the triggered controlled release of iodine, an antimicrobial element that does not generate resistance. It comprises beads of the iodophilic MOF UiO-66 containing encapsulated gold nanorods (AuNRs) coated with a silica shell. Irradiation of the AuNRs with near-infrared light (NIR) provokes a photothermal effect and the resultant heat actively liberates the iodine. After validating the performance of this composite, it is integrated into a polymer for the development of antibacterial films. This work assesses the adsorption of iodine into these composite films, as well as its passive long-term release and active light-triggered. Finally, this work validates the antibacterial activity of the composite films in vitro against gram-positive and gram-negative bacteria. The findings will surely inform the development of new prophylactic treatments.

Date of online publication

02.02.2022

Pages (from - to)

2112902 - 1 - 2112902 - 12

DOI

10.1002/adfm.202112902

URL

https://onlinelibrary.wiley.com/doi/full/10.1002/adfm.202112902

Comments

Article Number: 2112902

Points of MNiSW / journal

200.0

Impact Factor

18.808 [List 2020]

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