Tripartite prodrugs as an example of multidirectional, programmable therapy
[ 1 ] Wydział Technologii Chemicznej, Politechnika Poznańska | [ 2 ] Instytut Technologii i Inżynierii Chemicznej, Wydział Technologii Chemicznej, Politechnika Poznańska | [ SzD ] doctoral school student | [ P ] employee
PL Proleki trójstronne jako przykład wielokierunkowej, programowalnej terapii
2023
abstract
english
- tripartite prodrugs
- programmable therapy
- cDDP
- piwampycilin
- anticancer therapies
EN Therapeutics with a prodrug approach, which is based on the introduction a derivative of an active substance that undergoes biotransformation in the target organ, are proving to be the answer to this problem. Triple-drug pro-drugs are an innovative group of therapeutics that incorporate several potential therapeutic substances. It is a state-of-the-art division that implies a versatile and multidirectional use of the structural components. They can undertake blocking, poisoning, cell growth-stimulating and intercellular transport-accelerating activities. Most of them find their use in interactions with DNA molecules, making it possible to counteract the development of cancers of various origins.
53 - 53
other
other
final published version
at the time of publication
public