New way to obtain the poly(L-lactide-co-D,L-lactide) blend filled with nanohydroxyapatite as biomaterial for 3D-printed bone-reconstruction implants
[ 1 ] Instytut Technologii Materiałów, Wydział Inżynierii Mechanicznej, Politechnika Poznańska | [ 2 ] Instytut Technologii i Inżynierii Chemicznej, Wydział Technologii Chemicznej, Politechnika Poznańska | [ P ] pracownik
[2.8] Inżynieria materiałowa[2.9] Inżynieria mechaniczna[7.6] Nauki chemiczne
2022
artykuł naukowy
angielski
- poly(L-lactide-co-D
- L-lactide)
- nanohydroxyapatite
- biocomposite
- co-rotating twin-screw extrusion
- bone-fixation material
EN A novel, bone-reconstruction dedicated polymeric-nanohydroxyapatite material has been prepared for 3D-printed implant. The composites of poly(L-lactide-co-D,L-lactide) (PLDLLA) and nanosized hydroxyapatite were prepared by a co-rotating twin-screw extrusion. Structural properties of the filler and polymeric blends were characterized by XRD (X-ray Powder Diffraction), SEM (Scanning Electron Microscopy), and EDS mapping (energy dispersive spectroscopy), FT-IR (Fourier-transformed infrared spectroscopy), and NMR (Nuclear Magnetic Resonance) technics. Molar masses of the composites at various preparation steps were also investigated. The structural studies and thermogravimetric analysis proved a successful preparation of the nanohydroxyapatite and its nanocomposites. Mechanical results in conjunction with density values, reported as close to human bone, evidenced usability of this novel material for internal bone fixation implant. Contact angle analysis showed favored growth of tissue on the biocomposite containing 10 wt% of the filler. The PLDLLA-based composite can be an excellent candidate for bone reconstruction implants due to their superior mechanical properties, bioactivity, and complete resorbability.
06.01.2022
110997-1 - 110997-9
Article Number: 110997
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